Title |
The Predictive Value of Inflammation-Related Peripheral Blood Measurements in Cancer Staging and Prognosis
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Published in |
Frontiers in oncology, March 2018
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DOI | 10.3389/fonc.2018.00078 |
Pubmed ID | |
Authors |
Joanna L. Sylman, Annachiara Mitrugno, Michelle Atallah, Garth W. Tormoen, Joseph J. Shatzel, Samuel Tassi Yunga, Todd H. Wagner, John T. Leppert, Parag Mallick, Owen J. T. McCarty |
Abstract |
In this review, we discuss the interaction between cancer and markers of inflammation (such as levels of inflammatory cells and proteins) in the circulation, and the potential benefits of routinely monitoring these markers in peripheral blood measurement assays. Next, we discuss the prognostic value and limitations of using inflammatory markers such as neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios and C-reactive protein measurements. Furthermore, the review discusses the benefits of combining multiple types of measurements and longitudinal tracking to improve staging and prognosis prediction of patients with cancer, and the ability of novel in silico frameworks to leverage this high-dimensional data. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 83 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 12% |
Student > Master | 8 | 10% |
Student > Bachelor | 7 | 8% |
Student > Postgraduate | 7 | 8% |
Student > Doctoral Student | 6 | 7% |
Other | 13 | 16% |
Unknown | 32 | 39% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 23 | 28% |
Biochemistry, Genetics and Molecular Biology | 9 | 11% |
Agricultural and Biological Sciences | 4 | 5% |
Nursing and Health Professions | 3 | 4% |
Immunology and Microbiology | 3 | 4% |
Other | 6 | 7% |
Unknown | 35 | 42% |