Title |
A Literature Review of Genetic Markers Conferring Impaired Response to Cardiovascular Drugs
|
---|---|
Published in |
American Journal of Cardiovascular Drugs, March 2018
|
DOI | 10.1007/s40256-018-0267-2 |
Pubmed ID | |
Authors |
Hitesh Shukla, Jessica Louise Mason, Abdullah Sabyah |
Abstract |
Pharmacogenetics is an emerging area of medicine, and more work is needed to fully integrate it into a clinical setting for the benefit of patients. Genetic markers can influence the action of many drugs, including those that prevent and treat cardiovascular conditions. Genotyping is not yet commonplace, but guidelines are being put in place to help practitioners determine the effect a genetic marker may have on certain drugs. With advancements in genetic technology and falling costs, genotyping could be available to all patients via a simple saliva test. This would be a cost-effective way for practitioners to determine the most effective treatment for individuals, reducing "trial and error," adverse effects, and rehospitalization rates and increasing patient compliance. Cardiovascular diseases are the leading causes of death worldwide, so using the most effective medication to treat or prevent them is of utmost importance in reducing incidence and mortality. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 20% |
Student > Bachelor | 4 | 16% |
Other | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Student > Ph. D. Student | 1 | 4% |
Other | 0 | 0% |
Unknown | 10 | 40% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 20% |
Nursing and Health Professions | 3 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Agricultural and Biological Sciences | 1 | 4% |
Other | 2 | 8% |
Unknown | 10 | 40% |