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Mendeley readers
Attention Score in Context
| Title |
Plasma Soluble Prion Protein, a Potential Biomarker for Sport-Related Concussions: A Pilot Study
|
|---|---|
| Published in |
PLOS ONE, February 2015
|
| DOI | 10.1371/journal.pone.0117286 |
| Pubmed ID | |
| Authors |
Nam Pham, Hungbo Akonasu, Rhonda Shishkin, Changiz Taghibiglou |
| Abstract |
Sport-related mild traumatic brain injury (mTBI) or concussion is a significant health concern to athletes with potential long-term consequences. The diagnosis of sport concussion and return to sport decision making is one of the greatest challenges facing health care clinicians working in sports. Blood biomarkers have recently demonstrated their potential in assisting the detection of brain injury particularly, in those cases with no obvious physical injury. We have recently discovered plasma soluble cellular prion protein (PrPC) as a potential reliable biomarker for blast induced TBI (bTBI) in a rodent animal model. In order to explore the application of this novel TBI biomarker to sport-related concussion, we conducted a pilot study at the University of Saskatchewan (U of S) by recruiting athlete and non-athlete 18 to 30 year-old students. Using a modified quantitative ELISA method, we first established normal values for the plasma soluble PrPC in male and female students. The measured plasma soluble PrPC in confirmed concussion cases demonstrated a significant elevation of this analyte in post-concussion samples. Data collected from our pilot study indicates that the plasma soluble PrPC is a potential biomarker for sport-related concussion, which may be further developed into a clinical diagnostic tool to assist clinicians in the assessment of sport concussion and return-to-play decision making. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 117 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 17 | 14% |
| Student > Master | 16 | 13% |
| Student > Ph. D. Student | 15 | 13% |
| Researcher | 14 | 12% |
| Student > Postgraduate | 8 | 7% |
| Other | 31 | 26% |
| Unknown | 18 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 24% |
| Sports and Recreations | 13 | 11% |
| Neuroscience | 11 | 9% |
| Biochemistry, Genetics and Molecular Biology | 9 | 8% |
| Agricultural and Biological Sciences | 8 | 7% |
| Other | 27 | 23% |
| Unknown | 22 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 March 2023.
All research outputs
#4,015,907
of 22,787,797 outputs
Outputs from PLOS ONE
#57,521
of 194,524 outputs
Outputs of similar age
#57,984
of 351,943 outputs
Outputs of similar age from PLOS ONE
#653
of 3,388 outputs
Altmetric has tracked 22,787,797 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 194,524 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,943 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 3,388 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.