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Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden…

Overview of attention for article published in Thrombosis Journal, January 2008
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  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

wikipedia
1 Wikipedia page

Citations

dimensions_citation
9 Dimensions

Readers on

mendeley
24 Mendeley
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Title
Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death
Published in
Thrombosis Journal, January 2008
DOI 10.1186/1477-9560-6-17
Pubmed ID
Authors

Yue-Mei Fan, Pekka J Karhunen, Mari Levula, Erkki Ilveskoski, Jussi Mikkelsson, Olli A Kajander, Otso Järvinen, Niku Oksala, Janita Thusberg, Mauno Vihinen, Juha-Pekka Salenius, Leena Kytömäki, Juhani T Soini, Reijo Laaksonen, Terho Lehtimäki

Abstract

Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcription factor 2 (SREBF-2) and the SREBF cleavage-activating protein (SCAP). We investigated whole genome expression in a series of human atherosclerotic samples from different vascular territories and studied whether the non-synonymous coding variants in the interacting domains of two genes, SREBF-2 1784G>C (rs2228314) and SCAP 2386A>G, are related to the progression of coronary atherosclerosis and the risk of pre-hospital sudden cardiac death (SCD).

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 8%
Sweden 1 4%
Unknown 21 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 25%
Researcher 4 17%
Professor 4 17%
Other 2 8%
Student > Bachelor 2 8%
Other 4 17%
Unknown 2 8%
Readers by discipline Count As %
Medicine and Dentistry 8 33%
Biochemistry, Genetics and Molecular Biology 6 25%
Agricultural and Biological Sciences 5 21%
Mathematics 1 4%
Unspecified 1 4%
Other 1 4%
Unknown 2 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2011.
All research outputs
#817,542
of 3,627,694 outputs
Outputs from Thrombosis Journal
#13
of 43 outputs
Outputs of similar age
#24,635
of 95,027 outputs
Outputs of similar age from Thrombosis Journal
#1
of 5 outputs
Altmetric has tracked 3,627,694 research outputs across all sources so far. This one has received more attention than most of these and is in the 63rd percentile.
So far Altmetric has tracked 43 research outputs from this source. They receive a mean Attention Score of 2.8. This one scored the same or higher as 30 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,027 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them