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Acylated Quinic Acids Are the Main Salicortin Metabolites in the Lepidopteran Specialist Herbivore Cerura vinula

Overview of attention for article published in Journal of Chemical Ecology, March 2018
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Title
Acylated Quinic Acids Are the Main Salicortin Metabolites in the Lepidopteran Specialist Herbivore Cerura vinula
Published in
Journal of Chemical Ecology, March 2018
DOI 10.1007/s10886-018-0945-1
Pubmed ID
Authors

Felix Feistel, Christian Paetz, Riya C. Menezes, Daniel Veit, Bernd Schneider

Abstract

Salicortin is a phenolic glucoside produced in Salicaceae as a chemical defense against herbivory. The specialist lepidopteran herbivorous larvae of Cerura vinula are able to overcome this defense. We examined the main frass constituents of C. vinula fed on Populus nigra leaves, and identified 11 quinic acid derivatives with benzoate and/or salicylate substitution. We asked whether the compounds are a result of salicortin breakdown and sought answers by carrying out feeding experiments with highly 13C-enriched salicortin. Using HRMS and NMR analyses, we were able to confirm that salicortin metabolism in C. vinula proceeds through deglucosylation and ester hydrolysis, after which saligenin is oxidatively transformed into salicylic acid and, eventually, conjugated to quinic acid. To the best of our knowledge, this is the first report of a detoxification pathway based on conjugation with quinic acid.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 24%
Student > Doctoral Student 2 12%
Researcher 2 12%
Student > Ph. D. Student 2 12%
Student > Bachelor 1 6%
Other 1 6%
Unknown 5 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 29%
Chemistry 3 18%
Pharmacology, Toxicology and Pharmaceutical Science 2 12%
Psychology 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Other 0 0%
Unknown 5 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2018.
All research outputs
#14,970,944
of 23,028,364 outputs
Outputs from Journal of Chemical Ecology
#1,570
of 2,055 outputs
Outputs of similar age
#217,258
of 359,612 outputs
Outputs of similar age from Journal of Chemical Ecology
#14
of 27 outputs
Altmetric has tracked 23,028,364 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,055 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,612 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.