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Role of Mineralocorticoid Receptors in Obstructive Sleep Apnea and Metabolic Syndrome

Overview of attention for article published in Current Hypertension Reports, March 2018
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Title
Role of Mineralocorticoid Receptors in Obstructive Sleep Apnea and Metabolic Syndrome
Published in
Current Hypertension Reports, March 2018
DOI 10.1007/s11906-018-0819-5
Pubmed ID
Authors

Badhma Valaiyapathi, David A. Calhoun

Abstract

This review will summarize recent developments in the research on the mineralocorticoid receptor and its impact on obstructive sleep apnea and metabolic syndrome. Aldosterone excess plays an important role in the association between resistant hypertension and obstructive sleep apnea. The prevalence of obesity is increasing rapidly worldwide and is especially common among patients with obstructive sleep apnea, resistant hypertension, and metabolic syndrome, suggesting probable mechanistic links between these three conditions. Mineralocorticoid receptor expression is increased in obese individuals, which may contribute to the common association between obesity and hyperaldosteronism. Mineralocorticoid receptor blockers reduce the severity of obstructive sleep apnea among resistant hypertension patients. A large body of literature demonstrates a strong association between obesity, hyperaldosteronism, resistant hypertension, and sleep apnea, including specific benefit of treatment with mineralocorticoid receptor blockers for these separate disorders.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 25%
Student > Bachelor 4 20%
Student > Doctoral Student 1 5%
Student > Ph. D. Student 1 5%
Student > Postgraduate 1 5%
Other 0 0%
Unknown 8 40%
Readers by discipline Count As %
Medicine and Dentistry 8 40%
Nursing and Health Professions 2 10%
Physics and Astronomy 1 5%
Agricultural and Biological Sciences 1 5%
Unknown 8 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2019.
All research outputs
#15,692,595
of 23,318,744 outputs
Outputs from Current Hypertension Reports
#471
of 739 outputs
Outputs of similar age
#213,249
of 333,139 outputs
Outputs of similar age from Current Hypertension Reports
#12
of 20 outputs
Altmetric has tracked 23,318,744 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 739 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,139 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.