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Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians

Overview of attention for article published in International Journal of Legal Medicine, February 2004
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3 Wikipedia pages

Citations

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164 Mendeley
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Title
Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians
Published in
International Journal of Legal Medicine, February 2004
DOI 10.1007/s00414-004-0427-6
Pubmed ID
Authors

Michael D. Coble, Rebecca S. Just, Jennifer E. O’Callaghan, Ilona H. Letmanyi, Christine T. Peterson, Jodi A. Irwin, Thomas J. Parsons

Abstract

We have sequenced the entire mtDNA genome (mtGenome) of 241 individuals who match 1 of 18 common European Caucasian HV1/HV2 types, to identify sites that permit additional forensic discrimination. We found that over the entire mtGenome even individuals with the same HV1/HV2 type rarely match. Restricting attention to sites that are neutral with respect to phenotypic expression, we have selected eight panels of single nucleotide polymorphism (SNP) sites that are useful for additional discrimination. These panels were selected to be suitable for multiplex SNP typing assays, with 7-11 sites per panel. The panels are specific for one or more of the common HV1/HV2 types (or closely related types), permitting a directed approach that conserves limiting case specimen extracts while providing a maximal chance for additional discrimination. Discrimination provided by the panels reduces the frequency of the most common type in the European Caucasian population from approximately 7% to approximately 2%, and the 18 common types we analyzed are resolved to 105 different types, 55 of which are seen only once.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 164 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
Thailand 2 1%
Brazil 1 <1%
Portugal 1 <1%
Australia 1 <1%
United States 1 <1%
Unknown 156 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 35 21%
Student > Ph. D. Student 33 20%
Student > Master 25 15%
Student > Bachelor 15 9%
Other 8 5%
Other 26 16%
Unknown 22 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 76 46%
Biochemistry, Genetics and Molecular Biology 41 25%
Medicine and Dentistry 5 3%
Social Sciences 3 2%
Computer Science 2 1%
Other 9 5%
Unknown 28 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2024.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from International Journal of Legal Medicine
#394
of 2,061 outputs
Outputs of similar age
#33,778
of 133,401 outputs
Outputs of similar age from International Journal of Legal Medicine
#3
of 4 outputs
Altmetric has tracked 22,788,370 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,061 research outputs from this source. They receive a mean Attention Score of 4.6. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 133,401 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.