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Centrosome and retroviruses: The dangerous liaisons

Overview of attention for article published in Retrovirology, April 2007
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2 Wikipedia pages

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77 Mendeley
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Title
Centrosome and retroviruses: The dangerous liaisons
Published in
Retrovirology, April 2007
DOI 10.1186/1742-4690-4-27
Pubmed ID
Authors

Philippe V Afonso, Alessia Zamborlini, Ali Saïb, Renaud Mahieux

Abstract

Centrosomes are the major microtubule organizing structures in vertebrate cells. They localize in close proximity to the nucleus for the duration of interphase and play major roles in numerous cell functions. Consequently, any deficiency in centrosome function or number may lead to genetic instability. Several viruses including retroviruses such as, Foamy Virus, HIV-1, JSRV, M-PMV and HTLV-1 have been shown to hamper centrosome functions for their own profit, but the outcomes are very different. Foamy viruses, HIV-1, JSRV, M-PMV and HTLV-1 use the cellular machinery to traffic towards the centrosome during early and/or late stages of the infection. In addition HIV-1 Vpr protein alters the cell-cycle regulation by hijacking centrosome functions. Enthrallingly, HTLV-1 Tax expression also targets the functions of the centrosome, and this event is correlated with centrosome amplification, aneuploidy and transformation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
France 1 1%
India 1 1%
Italy 1 1%
Mexico 1 1%
Canada 1 1%
Unknown 70 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 23%
Researcher 18 23%
Student > Master 11 14%
Student > Doctoral Student 4 5%
Professor > Associate Professor 4 5%
Other 11 14%
Unknown 11 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 41 53%
Biochemistry, Genetics and Molecular Biology 12 16%
Medicine and Dentistry 6 8%
Immunology and Microbiology 4 5%
Chemistry 2 3%
Other 2 3%
Unknown 10 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2021.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from Retrovirology
#408
of 1,106 outputs
Outputs of similar age
#26,519
of 75,148 outputs
Outputs of similar age from Retrovirology
#3
of 3 outputs
Altmetric has tracked 22,788,370 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 75,148 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.