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The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cells

Overview of attention for article published in Breast Cancer Research, July 2007
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

Mentioned by

patent
2 patents
wikipedia
2 Wikipedia pages

Citations

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17 Dimensions

Readers on

mendeley
33 Mendeley
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Title
The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cells
Published in
Breast Cancer Research, July 2007
DOI 10.1186/bcr1743
Pubmed ID
Authors

Youqi Han, Serban San-Marina, Lin Yang, Haytham Khoury, Mark D Minden

Abstract

There is growing evidence that the Wilms' tumor 1 suppressor gene (WT1) behaves as an oncogene in some forms of breast cancer. Previous studies have demonstrated that the N-terminal domain of WT1 can act as a dominant negative through self-association. In the studies presented here we have explored the potential for the zinc finger domain (ZF) of WT1 to also have dominant-negative effects, and thus further our understanding of this protein.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Unknown 32 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 27%
Student > Bachelor 7 21%
Researcher 5 15%
Student > Master 3 9%
Professor 2 6%
Other 3 9%
Unknown 4 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 42%
Biochemistry, Genetics and Molecular Biology 10 30%
Computer Science 2 6%
Veterinary Science and Veterinary Medicine 1 3%
Medicine and Dentistry 1 3%
Other 1 3%
Unknown 4 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2022.
All research outputs
#5,447,195
of 25,374,917 outputs
Outputs from Breast Cancer Research
#643
of 2,053 outputs
Outputs of similar age
#15,344
of 78,330 outputs
Outputs of similar age from Breast Cancer Research
#4
of 13 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 78,330 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.