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Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

Overview of attention for article published in BMC Genomics, June 2006
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Title
Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins
Published in
BMC Genomics, June 2006
DOI 10.1186/1471-2164-7-155
Pubmed ID
Authors

Yu-Hui Hu, Hans-Jörg Warnatz, Dominique Vanhecke, Florian Wagner, Andrea Fiebitz, Sabine Thamm, Pascal Kahlem, Hans Lehrach, Marie-Laure Yaspo, Michal Janitz

Abstract

Trisomy of human chromosome 21 (Chr21) results in Down's syndrome, a complex developmental and neurodegenerative disease. Molecular analysis of Down's syndrome, however, poses a particular challenge, because the aneuploid region of Chr21 contains many genes of unknown function. Subcellular localization of human Chr21 proteins may contribute to further understanding of the functions and regulatory mechanisms of the genes that code for these proteins. Following this idea, we used a transfected-cell array technique to perform a rapid and cost-effective analysis of the intracellular distribution of Chr 21 proteins.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 6%
Belgium 1 3%
Unknown 32 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 31%
Researcher 6 17%
Student > Master 4 11%
Student > Bachelor 2 6%
Lecturer 2 6%
Other 6 17%
Unknown 4 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 43%
Biochemistry, Genetics and Molecular Biology 5 14%
Engineering 3 9%
Psychology 2 6%
Nursing and Health Professions 1 3%
Other 6 17%
Unknown 3 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2022.
All research outputs
#7,456,970
of 22,797,621 outputs
Outputs from BMC Genomics
#3,599
of 10,648 outputs
Outputs of similar age
#18,605
of 52,755 outputs
Outputs of similar age from BMC Genomics
#17
of 36 outputs
Altmetric has tracked 22,797,621 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,648 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 52,755 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.