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Mst1-FoxO Signaling Protects Naïve T Lymphocytes from Cellular Oxidative Stress in Mice

Overview of attention for article published in PLOS ONE, November 2009
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Title
Mst1-FoxO Signaling Protects Naïve T Lymphocytes from Cellular Oxidative Stress in Mice
Published in
PLOS ONE, November 2009
DOI 10.1371/journal.pone.0008011
Pubmed ID
Authors

Juhyun Choi, Sangphil Oh, Dongjun Lee, Hyun Jung Oh, Jik Young Park, Sean Bong Lee, Dae-Sik Lim

Abstract

The Ste-20 family kinase Hippo restricts cell proliferation and promotes apoptosis for proper organ development in Drosophila. In C. elegans, Hippo homolog also regulates longevity. The mammalian Ste20-like protein kinase, Mst1, plays a role in apoptosis induced by various types of apoptotic stress. Mst1 also regulates peripheral naïve T cell trafficking and proliferation in mice. However, its functions in mammals are not fully understood.

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Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
United States 1 1%
Poland 1 1%
China 1 1%
Unknown 67 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 24%
Researcher 13 18%
Student > Master 9 13%
Professor > Associate Professor 5 7%
Professor 4 6%
Other 11 15%
Unknown 12 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 37%
Medicine and Dentistry 10 14%
Biochemistry, Genetics and Molecular Biology 10 14%
Immunology and Microbiology 5 7%
Engineering 2 3%
Other 1 1%
Unknown 17 24%