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Mendeley readers
Attention Score in Context
| Title |
GPR30, the Non-Classical Membrane G Protein Related Estrogen Receptor, Is Overexpressed in Human Seminoma and Promotes Seminoma Cell Proliferation
|
|---|---|
| Published in |
PLOS ONE, April 2012
|
| DOI | 10.1371/journal.pone.0034672 |
| Pubmed ID | |
| Authors |
Nicolas Chevalier, Aurélie Vega, Adil Bouskine, Bénazir Siddeek, Jean-François Michiels, Daniel Chevallier, Patrick Fénichel |
| Abstract |
Testicular germ cell tumours are the most frequent cancer of young men with an increasing incidence all over the world. Pathogenesis and reasons of this increase remain unknown but epidemiological and clinical data have suggested that fetal exposure to environmental endocrine disruptors (EEDs) with estrogenic effects, could participate to testicular germ cell carcinogenesis. However, these EEDs (like bisphenol A) are often weak ligands for classical nuclear estrogen receptors. Several research groups recently showed that the non classical membrane G-protein coupled estrogen receptor (GPER/GPR30) mediates the effects of estrogens and several xenoestrogens through rapid non genomic activation of signal transduction pathways in various human estrogen dependent cancer cells (breast, ovary, endometrium). The aim of this study was to demonstrate that GPER was overexpressed in testicular tumours and was able to trigger JKT-1 seminoma cell proliferation. |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| India | 1 | 1% |
| Austria | 1 | 1% |
| Unknown | 65 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 19% |
| Student > Ph. D. Student | 11 | 16% |
| Student > Master | 10 | 14% |
| Student > Doctoral Student | 6 | 9% |
| Student > Bachelor | 6 | 9% |
| Other | 12 | 17% |
| Unknown | 11 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 22 | 32% |
| Agricultural and Biological Sciences | 14 | 20% |
| Medicine and Dentistry | 11 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 6% |
| Environmental Science | 2 | 3% |
| Other | 4 | 6% |
| Unknown | 12 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2023.
All research outputs
#5,224,784
of 24,619,469 outputs
Outputs from PLOS ONE
#80,680
of 212,830 outputs
Outputs of similar age
#33,240
of 165,146 outputs
Outputs of similar age from PLOS ONE
#970
of 3,725 outputs
Altmetric has tracked 24,619,469 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 212,830 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,146 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 3,725 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.