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Mendeley readers
| Chapter title |
Virological and Cellular Roles of the Transcriptional Coactivator LEDGF/p75
|
|---|---|
| Chapter number | 7 |
| Book title |
HIV Interactions with Host Cell Proteins
|
| Published in |
Current topics in microbiology and immunology, February 2015
|
| DOI | 10.1007/978-3-642-02175-6_7 |
| Pubmed ID | |
| Book ISBNs |
978-3-64-202174-9, 978-3-64-202175-6
|
| Authors |
Manual Llano, James Morrison, Eric M. Poeschla, Manuel Llano, Llano, Manuel, Morrison, James, Poeschla, Eric M. |
| Abstract |
The chromatin-associated cellular proteins LEDGF/p75 and LEDGF/p52 have been implicated in transcriptional regulation, cell survival and autoimmunity. LEDGF/p75 also appears to act as a chromatin-docking factor or receptor for HIV-1 and other lentiviruses and to play a role in leukemogenesis. For both the viral and cellular roles of this protein, a key feature is its ability to act as a molecular adaptor and tether proteins to the chromatin fiber. This chapter reviews the emerging roles of LEDGF/p75 and LEDGF/p52 in diverse cellular processes and disease states. |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 18 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 28% |
| Student > Bachelor | 3 | 17% |
| Student > Doctoral Student | 2 | 11% |
| Researcher | 2 | 11% |
| Student > Master | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 4 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 22% |
| Agricultural and Biological Sciences | 3 | 17% |
| Medicine and Dentistry | 2 | 11% |
| Business, Management and Accounting | 1 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 6 | 33% |