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Broad Clade 2 Cross-Reactive Immunity Induced by an Adjuvanted Clade 1 rH5N1 Pandemic Influenza Vaccine

Overview of attention for article published in PLOS ONE, February 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

patent
6 patents
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
143 Dimensions

Readers on

mendeley
55 Mendeley
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1 Connotea
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Title
Broad Clade 2 Cross-Reactive Immunity Induced by an Adjuvanted Clade 1 rH5N1 Pandemic Influenza Vaccine
Published in
PLOS ONE, February 2008
DOI 10.1371/journal.pone.0001665
Pubmed ID
Authors

Isabel Leroux-Roels, Roger Bernhard, Pascal Gérard, Mamadou Dramé, Emmanuel Hanon, Geert Leroux-Roels

Abstract

The availability of H5N1 vaccines that can elicit a broad cross-protective immunity against different currently circulating clade 2 H5N1 viruses is a pre-requisite for the development of a successful pre-pandemic vaccination strategy. In this regard, it has recently been shown that adjuvantation of a recombinant clade 1 H5N1 inactivated split-virion vaccine with an oil-in-water emulsion-based adjuvant system also promoted cross-immunity against a recent clade 2 H5N1 isolate (A/Indonesia/5/2005, subclade 2.1). Here we further analyse the cross-protective potential of the vaccine against two other recent clade 2 isolates (A/turkey/Turkey/1/2005 and A/Anhui/1/2005 which are, as defined by WHO, representatives of subclades 2.2 and 2.3 respectively).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 2%
Bangladesh 1 2%
South Africa 1 2%
Unknown 52 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 20%
Researcher 11 20%
Student > Master 6 11%
Student > Bachelor 5 9%
Professor 3 5%
Other 10 18%
Unknown 9 16%
Readers by discipline Count As %
Medicine and Dentistry 13 24%
Agricultural and Biological Sciences 12 22%
Biochemistry, Genetics and Molecular Biology 4 7%
Nursing and Health Professions 2 4%
Immunology and Microbiology 2 4%
Other 12 22%
Unknown 10 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2024.
All research outputs
#2,530,630
of 23,292,144 outputs
Outputs from PLOS ONE
#32,174
of 199,063 outputs
Outputs of similar age
#6,999
of 80,272 outputs
Outputs of similar age from PLOS ONE
#64
of 282 outputs
Altmetric has tracked 23,292,144 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 199,063 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.2. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 80,272 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 282 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.