Chapter title |
Vitamin D, Cardiovascular Disease and Risk Factors
|
---|---|
Chapter number | 18 |
Book title |
Ultraviolet Light in Human Health, Diseases and Environment
|
Published in |
Advances in experimental medicine and biology, January 2017
|
DOI | 10.1007/978-3-319-56017-5_18 |
Pubmed ID | |
Book ISBNs |
978-3-31-956016-8, 978-3-31-956017-5
|
Authors |
Tea Skaaby, Betina H. Thuesen, Allan Linneberg, Skaaby, Tea, Thuesen, Betina H., Linneberg, Allan |
Abstract |
Observational studies have suggested a possible protective role of vitamin D on the cardiovascular system. The available evidence does not support either cardiovascular benefits or harms of vitamin D supplementation. This chapter provides an overview and discussion of the current knowledge of vitamin D effects from a cardiovascular health perspective. It focuses on vitamin D in relation to cardiovascular disease, i.e. ischemic heart disease, and stroke; the traditional cardiovascular risk factors hypertension, abnormal blood lipids, obesity; and the emerging risk factors hyperparathyroidism, microalbuminuria, chronic obstructive pulmonary diseases, and non-alcoholic fatty liver disease. Meta-analyses of observational studies have largely found vitamin D levels to be inversely associated with cardiovascular risk and disease. However, Mendelian randomization studies and randomized, controlled trials (RCTs) have not been able to consistently replicate the observational findings. Several RCTs are ongoing, and the results from these are needed to clarify whether vitamin D deficiency is a causal and reversible factor to prevent cardiovascular disease. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 100 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 11% |
Researcher | 10 | 10% |
Student > Master | 9 | 9% |
Other | 8 | 8% |
Student > Doctoral Student | 5 | 5% |
Other | 15 | 15% |
Unknown | 42 | 42% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 21% |
Nursing and Health Professions | 14 | 14% |
Biochemistry, Genetics and Molecular Biology | 5 | 5% |
Agricultural and Biological Sciences | 4 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Other | 7 | 7% |
Unknown | 47 | 47% |