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Suppression and Regulation of Immune Responses

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Cover of 'Suppression and Regulation of Immune Responses'

Table of Contents

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    Book Overview
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    Chapter 1 HLA-G as an Inhibitor of Immune Responses
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    Chapter 2 New Molecular and Cellular Mechanisms of Tolerance: Tolerogenic Actions of IL-2.
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    Chapter 3 Expansion of Regulatory T Cells In Vitro and In Vivo by IL-33.
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    Chapter 4 Standardization, Evaluation, and Area-Under-Curve Analysis of Human and Murine Treg Suppressive Function.
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    Chapter 5 Suppression and Regulation of Immune Responses
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    Chapter 6 Generation and Characterization of Mouse Regulatory Macrophages
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    Chapter 7 Generation and Expansion of T Helper 17 Lymphocytes Ex Vivo
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    Chapter 8 Autoimmune Diabetes: An Overview of Experimental Models and Novel Therapeutics
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    Chapter 9 Recent Advances in the Treatment of Immune-Mediated Inflammatory Diseases
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    Chapter 10 Application of Humanized Mice in Immunological Research
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    Chapter 11 Humanized Mice as Preclinical Models in Transplantation
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    Chapter 12 Dextran Sulfate Sodium (DSS)-Induced Acute Colitis in the Rat.
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    Chapter 13 Corneal Immunosuppressive Mechanisms, Anterior Chamber-Associated Immune Deviation (ACAID) and Their Role in Allograft Rejection
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    Chapter 14 Food Allergies: Novel Mechanisms and Therapeutic Perspectives.
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    Chapter 15 Standardized Multi-Color Flow Cytometry and Computational Biomarker Discovery
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    Chapter 16 The Aryl Hydrocarbon Receptor in Immunity: Tools and Potential.
Attention for Chapter 9: Recent Advances in the Treatment of Immune-Mediated Inflammatory Diseases
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Chapter title
Recent Advances in the Treatment of Immune-Mediated Inflammatory Diseases
Chapter number 9
Book title
Suppression and Regulation of Immune Responses
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3139-2_9
Pubmed ID
Book ISBNs
978-1-4939-3138-5, 978-1-4939-3139-2
Authors

Sander W. Tas, Dominique L. P. Baeten, Tas, Sander W., Baeten, Dominique L. P.

Abstract

The treatment of immune-mediated inflammatory diseases (IMIDs) has dramatically improved over the last two decades by the development of a series of targeted biological therapies. This paper focuses on new developments in the treatment of IMIDs. In particular, we discuss how different ways of targeting the same mediators can lead to different efficacy and safety profiles, using B cell targeting as example. In addition, we discuss the emerging field of 'small molecules' that target specifically intracellular processes related to cytokine signaling, cell activation, cell migration, and other processes relevant to tissue inflammation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 1 25%
Researcher 1 25%
Other 1 25%
Student > Master 1 25%
Readers by discipline Count As %
Immunology and Microbiology 2 50%
Agricultural and Biological Sciences 1 25%
Biochemistry, Genetics and Molecular Biology 1 25%