Chapter title |
Marihuana vs. alcohol: a pharmacologic comparison.
|
---|---|
Chapter number | 15 |
Book title |
Biochemical Pharmacology of Ethanol
|
Published in |
Advances in experimental medicine and biology, January 1975
|
DOI | 10.1007/978-1-4684-7529-6_15 |
Pubmed ID | |
Book ISBNs |
978-1-4684-7531-9, 978-1-4684-7529-6
|
Authors |
E B Truitt, Truitt, Edward B. |
Abstract |
A review of the pharmacology, behavior, toxicity and therapeutic actions of alcohol and marihuana shows many similarities between the two drugs and few striking differences. Both drugs have fundamental non-specific actions on the neural membrane in common with the sedative-hypnotic-anesthetic group of drugs. They differ mainly in the quantitative aspects of their action owing to variation in 1) the ratio of stimulant to depressant effects, 2) their distribution in the body because of the greater lipid solubility of delta-9-tetrahydrocannabinol (delta-9THC), 3) the route of intake and 4) in their metabolic transformation. Despite marked contrasts in potency, toxicity and therapeutic potential as a result of these differences it is proposed that the proper pharmacologic classification of both drugs is in the sedative group based on their activity at non-toxic levels rather than regarding marihuana as a primary hallucinogen as presently done in many texts. |
X Demographics
Geographical breakdown
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Argentina | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 21% |
Other | 3 | 16% |
Student > Ph. D. Student | 2 | 11% |
Researcher | 2 | 11% |
Student > Master | 1 | 5% |
Other | 3 | 16% |
Unknown | 4 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 3 | 16% |
Psychology | 3 | 16% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Agricultural and Biological Sciences | 2 | 11% |
Chemical Engineering | 1 | 5% |
Other | 4 | 21% |
Unknown | 4 | 21% |