Chapter 1 Biocomputational Strategies for Microbial Drug Target Identification

Chapter 2 Methods to assay inhibitors of DNA gyrase and topoisomerase IV activities.

Chapter 3 A Method to Assay Inhibitors of DNA Polymerase IIIC Activity

Chapter 4 Methods to Identify and Characterize Inhibitors of Bacterial RNA Polymerase

Chapter 5 Methods to Assay Inhibitors of tRNA Synthetase Activity

Chapter 6 Three Methods to Assay Inhibitors of Ribosomal Subunit Assembly

Chapter 7 Inhibition ofChaperone-Dependent Bacterial Ribosome Biogenesis

Chapter 8 Assays for the Identification of Inhibitors Targeting Specific Translational Steps

Chapter 9 SPARK: A New Peptidyl Transferase Activity Assay

Chapter 10 High-Throughput Screening of Peptide Deformylase Inhibitors

Chapter 11 A Method to Assay Penicillin-Binding Proteins

Chapter 12 A Method to Assay Inhibitors of Lipopolysaccharide Synthesis

Chapter 13 Methods for Assessing the Structure and Function of Cationic Antimicrobial Peptides

Chapter 14 Flow Cytometry of Bacterial Membrane Potential and Permeability

Chapter 15 Bacterial efflux pump inhibitors.

Chapter 16 Mycobacterium tuberculosis β-Ketoacyl Acyl Carrier Protein Synthase III (mtFabH) Assay: Principles and Method

Chapter 17 Screening for Compounds That Affect the Interaction Between Bacterial Two-Component Signal Transduction Response Regulator Protein and Cognate Promoter DNA

Chapter 18 The Activity of rRNA Resistance Methyltransferases Assessed by MALDI Mass Spectrometry

Chapter 19 Assays for Β-Lactamase Activity and Inhibition

Chapter 20 Studies of Enzymes That Cause Resistance to Aminoglycosides Antibiotics