Title |
Whole-genome sequencing and identification of Morganella morganii KT pathogenicity-related genes
|
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Published in |
BMC Genomics, December 2012
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DOI | 10.1186/1471-2164-13-s7-s4 |
Pubmed ID | |
Authors |
Yu-Tin Chen, Hwei-Ling Peng, Wei-Chung Shia, Fang-Rong Hsu, Chuian-Fu Ken, Yu-Ming Tsao, Chang-Hua Chen, Chun-Eng Liu, Ming-Feng Hsieh, Huang-Chi Chen, Chuan-Yi Tang, Tien-Hsiung Ku |
Abstract |
The opportunistic enterobacterium, Morganella morganii, which can cause bacteraemia, is the ninth most prevalent cause of clinical infections in patients at Changhua Christian Hospital, Taiwan. The KT strain of M. morganii was isolated during postoperative care of a cancer patient with a gallbladder stone who developed sepsis caused by bacteraemia. M. morganii is sometimes encountered in nosocomial settings and has been causally linked to catheter-associated bacteriuria, complex infections of the urinary and/or hepatobiliary tracts, wound infection, and septicaemia. M. morganii infection is associated with a high mortality rate, although most patients respond well to appropriate antibiotic therapy. To obtain insights into the genome biology of M. morganii and the mechanisms underlying its pathogenicity, we used Illumina technology to sequence the genome of the KT strain and compared its sequence with the genome sequences of related bacteria. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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India | 1 | 1% |
France | 1 | 1% |
Unknown | 97 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 20 | 20% |
Student > Ph. D. Student | 15 | 15% |
Student > Master | 13 | 13% |
Researcher | 10 | 10% |
Student > Doctoral Student | 8 | 8% |
Other | 11 | 11% |
Unknown | 22 | 22% |
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---|---|---|
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Biochemistry, Genetics and Molecular Biology | 21 | 21% |
Medicine and Dentistry | 10 | 10% |
Immunology and Microbiology | 8 | 8% |
Veterinary Science and Veterinary Medicine | 5 | 5% |
Other | 6 | 6% |
Unknown | 27 | 27% |