| Chapter title |
Structure and replication of hepatitis delta virus RNA.
|
|---|---|
| Chapter number | 1 |
| Book title |
Hepatitis Delta Virus
|
| Published in |
Current topics in microbiology and immunology, August 2006
|
| DOI | 10.1007/3-540-29802-9_1 |
| Pubmed ID | |
| Book ISBNs |
978-3-54-029801-4, 978-3-54-029802-1
|
| Authors |
J. M. Taylor, Taylor, J. M. |
| Abstract |
While this volume covers many different aspects of hepatitis delta virus (HDV) replication, the focus in this chapter is on studies of the structure and replication of the HDV RNA genome. An evaluation of such studies is not only an integral part of our understanding of HDV infections but it also sheds new light on some important aspects of cell biology, such as the fidelity of RNA transcription by a host RNA polymerase and on various forms of post-transcriptional RNA processing. Representations of the replication of the RNA genome are frequently simplified to a form of rolling-circle model, analogous to what have been described for plant viroids. One theme of this review is that such models, even after some revision, deceptively simplify the complexity of HDV replication and can fail to make clear major questions yet to be solved. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 2 | 4% |
| Uzbekistan | 1 | 2% |
| Unknown | 48 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 25% |
| Student > Master | 11 | 22% |
| Student > Bachelor | 8 | 16% |
| Student > Ph. D. Student | 8 | 16% |
| Student > Doctoral Student | 1 | 2% |
| Other | 5 | 10% |
| Unknown | 5 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 33% |
| Biochemistry, Genetics and Molecular Biology | 10 | 20% |
| Medicine and Dentistry | 8 | 16% |
| Immunology and Microbiology | 5 | 10% |
| Nursing and Health Professions | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 5 | 10% |