Chapter title |
The Extracellular Matrix of Fungal Biofilms
|
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Chapter number | 6 |
Book title |
Fungal Biofilms and related infections
|
Published in |
Advances in experimental medicine and biology, June 2016
|
DOI | 10.1007/5584_2016_6 |
Pubmed ID | |
Book ISBNs |
978-3-31-942359-3, 978-3-31-942360-9
|
Authors |
Mitchell, Kaitlin F, Zarnowski, Robert, Andes, David R, Kaitlin F. Mitchell, Robert Zarnowski, David R. Andes, Mitchell, Kaitlin F., Andes, David R. |
Abstract |
A key feature of biofilms is their production of an extracellular matrix. This material covers the biofilm cells, providing a protective barrier to the surrounding environment. During an infection setting, this can include such offenses as host cells and products of the immune system as well as drugs used for treatment. Studies over the past two decades have revealed the matrix from different biofilm species to be as diverse as the microbes themselves. This chapter will review the composition and roles of matrix from fungal biofilms, with primary focus on Candida species, Saccharomyces cerevisiae, Aspergillus fumigatus, and Cryptococcus neoformans. Additional coverage will be provided on the antifungal resistance proffered by the Candida albicans matrix, which has been studied in the most depth. A brief section on the matrix produced by bacterial biofilms will be provided for comparison. Current tools for studying the matrix will also be discussed, as well as suggestions for areas of future study in this field. |
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Geographical breakdown
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 99 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 14 | 14% |
Researcher | 13 | 13% |
Student > Ph. D. Student | 11 | 11% |
Student > Bachelor | 11 | 11% |
Student > Doctoral Student | 5 | 5% |
Other | 14 | 14% |
Unknown | 31 | 31% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 22 | 22% |
Biochemistry, Genetics and Molecular Biology | 19 | 19% |
Medicine and Dentistry | 9 | 9% |
Immunology and Microbiology | 4 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Other | 7 | 7% |
Unknown | 36 | 36% |