| Chapter title |
Capillary electrophoresis for pharmaceutical analysis.
|
|---|---|
| Chapter number | 10 |
| Book title |
Capillary Electrophoresis
|
| Published in |
Methods in molecular biology, April 2008
|
| DOI | 10.1007/978-1-59745-376-9_10 |
| Pubmed ID | |
| Book ISBNs |
978-1-58829-539-2, 978-1-59745-376-9
|
| Authors |
Alex Marsh, Margo Broderick, Kevin Altria, Joe Power, Sheila Donegan, Brian Clark, Marsh, Alex, Broderick, Margo, Altria, Kevin, Power, Joe, Donegan, Sheila, Clark, Brian |
| Abstract |
This chapter describes the application of capillary electrophoresis (CE) to pharmaceutical analysis. The areas of pharmaceutical analysis covered are enantiomer separation, analysis of small molecules such as amino acids or drug counter-ions, pharmaceutical assay, related substances determinations, and physiochemical measurements such as log P and pKa of compounds. The different electrophoretic modes available and their advantages for pharmaceutical analysis are described. Recent applications of CE for each subject area are tabulated with electrolyte details. Information on electrolyte choice and method optimization to obtain optimal separations is included. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 2% |
| Russia | 1 | 2% |
| Unknown | 52 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 22% |
| Student > Master | 8 | 15% |
| Student > Bachelor | 7 | 13% |
| Student > Doctoral Student | 6 | 11% |
| Researcher | 6 | 11% |
| Other | 6 | 11% |
| Unknown | 9 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 20 | 37% |
| Biochemistry, Genetics and Molecular Biology | 5 | 9% |
| Engineering | 5 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
| Medicine and Dentistry | 3 | 6% |
| Other | 10 | 19% |
| Unknown | 8 | 15% |