Chapter title |
Evaluation of Laryngopharyngeal Reflux in Pediatric Patients with Asthma Using a New Technique of Pharyngeal pH-Monitoring.
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Chapter number | 12 |
Book title |
Respiratory Regulation - Clinical Advances
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Published in |
Advances in experimental medicine and biology, January 2013
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DOI | 10.1007/978-94-007-4546-9_12 |
Pubmed ID | |
Book ISBNs |
978-9-40-074545-2, 978-9-40-074546-9
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Authors |
A. Banaszkiewicz, L. Dembinski, A. Zawadzka-Krajewska, M. Dziekiewicz, P. Albrecht, M. Kulus, A. Radzikowski, Banaszkiewicz, A., Dembinski, L., Zawadzka-Krajewska, A., Dziekiewicz, M., Albrecht, P., Kulus, M., Radzikowski, A. |
Abstract |
There is a debate about the association between asthma and gastroesophageal and/or laryngopharyngeal reflux (LPR). Pharyngeal pH-monitoring is a new technique that allows a physician to assess whether reflux passes the upper esophageal sphincter barrier. The aim of the study was to assess the prevalence of LPR in children with difficult-to-treat asthma. The present study was an open, prospective one. A total of 21 subjects of the mean age 12.7 years were enrolled in the study. All children were asked to fill out a Reflux Symptoms Index questionnaire and a 24-h pharyngeal pH monitoring was performed, using the Dx-pH Measurement System. The LPR was diagnosed in 13 (61.9%) children. There was a positive correlation between LPR diagnosis and the degree of asthma control. The LPR was more frequent in children treated with a higher than lower doses of fluticasone (p = 0.019, OR = 17.3) and in those using montelukast compared with non-users (p = 0.008, OR = 19.0). The mean Reflux Symptoms Index score was almost twice greater in children with LPR than in those without it (13.2 vs. 6.8, respectively, p = 0.003). We conclude that the prevalence of laryngopharyngeal reflux in children with difficult-to-treat asthma is substantial. |
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Mendeley readers
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Other | 3 | 14% |
Researcher | 3 | 14% |
Student > Postgraduate | 3 | 14% |
Student > Master | 3 | 14% |
Student > Bachelor | 2 | 10% |
Other | 2 | 10% |
Unknown | 5 | 24% |
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Immunology and Microbiology | 1 | 5% |
Engineering | 1 | 5% |
Unknown | 5 | 24% |