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Neurotrophic Factors

Overview of attention for book
Cover of 'Neurotrophic Factors'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Neurotrophic Factors: An Overview
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    Chapter 2 Ocular Nerve Growth Factor (NGF) and NGF Eye Drop Application as Paradigms to Investigate NGF Neuroprotective and Reparative Actions
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    Chapter 3 Culture of Rodent Cortical, Hippocampal, and Striatal Neurons
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    Chapter 4 Culture of Neonatal Rodent Microglia, Astrocytes, and Oligodendrocytes from the Cortex, Spinal Cord, and Cerebellum
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    Chapter 5 Central Nervous System Neuron-Glia co-Culture Models and Application to Neuroprotective Agents
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    Chapter 6 Preparation of Adult Rat Sensory Neuron Cultures and Their Application to Growth Cone Turning Assays
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    Chapter 7 Sensory Neurons from Tau Transgenic Mice and Their Utility in Drug Screening
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    Chapter 8 Culture of Rat Mesencephalic Dopaminergic Neurons and Application to Neurotoxic and Neuroprotective Agents
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    Chapter 9 Culture of Neurons and Smooth Muscle Cells from the Myenteric Plexus of Adult Mice
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    Chapter 10 Astrocyte/Microglia Cocultures as a Model to Study Neuroinflammation
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    Chapter 11 Micropatterned Geometry Shape Oligodendrocyte and Microglia Plasticity
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    Chapter 12 Oligodendrocyte Progenitor Cell Cultures: A Model to Screen Neurotrophic Compounds for Myelin Repair
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    Chapter 13 Cell Enumeration Assays: Application of the MTT and Sulforhodamine B Assays to Lipopolysaccharide-Stimulated Neonatal Rodent Microglia
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    Chapter 14 Diolistic Labeling and Analysis of Dendritic Spines
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    Chapter 15 Culture of Mouse Giant Central Nervous System Synapses and Application for Imaging and Electrophysiological Analyses
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    Chapter 16 Methods for Quantitative Analysis of Axonal Cargo Transport
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    Chapter 17 Neuronal Cell Morphology in Primary Cerebellar Granule Cells Using High-Content Analysis
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    Chapter 18 Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay
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    Chapter 19 Nerve Growth Factor-Induced Angiogenesis: 2. The Quail Chorioallantoic Membrane Assay
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    Chapter 20 Rat Pancreatic Beta-Cell Culture
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    Chapter 21 Growth and Neurotrophic Factors in Embryonic Stem Cells
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    Chapter 22 Site-Specific Direct Labeling of Neurotrophins and Their Receptors: From Biochemistry to Advanced Imaging Applications
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    Chapter 23 Isolation and Culture of Brain Microvascular Endothelial Cells for In Vitro Blood-Brain Barrier Studies
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    Chapter 24 Preparation of Rat Hippocampal Organotypic Cultures and Application to Study Amyloid β-Peptide Toxicity
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    Chapter 25 An Animal Model of Alzheimer Disease Based on the Intrahippocampal Injection of Amyloid β-Peptide (1–42)
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    Chapter 26 Active Induction of Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice
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    Chapter 27 A Model of Systemic Inflammation to Study Neuroinflammation
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    Chapter 28 Spared Nerve Injury as a Long-Lasting Model of Neuropathic Pain
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    Chapter 29 An In Vivo Compression Model of Spinal Cord Injury
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    Chapter 30 A Controlled Cortical Impact Preclinical Model of Traumatic Brain Injury
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    Chapter 31 Middle Cerebral Artery Occlusion by an Intraluminal Suture Method
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    Chapter 32 Primary Motor Neuron Culture to Promote Cellular Viability and Myelination
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    Chapter 33 Culture of Human Primary Bone Cells and Phenotype Assessment
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    Chapter 34 Recreating Intestinal Peristalsis in the Petri Dish
  36. Altmetric Badge
    Chapter 35 Synthesis of Biocompatible Titanate Nanofibers for Effective Delivery of Neuroprotective Agents
  37. Altmetric Badge
    Chapter 36 Preparation and Characterization of Biocompatible Chitosan Nanoparticles for Targeted Brain Delivery of Peptides
Attention for Chapter 25: An Animal Model of Alzheimer Disease Based on the Intrahippocampal Injection of Amyloid β-Peptide (1–42)
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

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1 Wikipedia page

Citations

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Chapter title
An Animal Model of Alzheimer Disease Based on the Intrahippocampal Injection of Amyloid β-Peptide (1–42)
Chapter number 25
Book title
Neurotrophic Factors
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7571-6_25
Pubmed ID
Book ISBNs
978-1-4939-7570-9, 978-1-4939-7571-6
Authors

Roberta Facchinetti, Maria Rosanna Bronzuoli, Caterina Scuderi, Facchinetti, Roberta, Bronzuoli, Maria Rosanna, Scuderi, Caterina

Abstract

The intrahippocampal injection of amyloid beta peptide (1-42) (Aβ(1-42)) represents one of the most useful animal models of Alzheimer disease. Since none of these available models fully represents the main pathological hallmarks of Alzheimer disease, stereotaxic Aβ(1-42) infusion provides researchers with an in vivo alternative paradigm. When performed by well-trained individuals, this model is the best-suited one for short-term studies focusing on the effects of Aβ(1-42) on a specific brain region or circuitry. Here, we describe all methodological phases of such a model.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 11 15%
Student > Ph. D. Student 8 11%
Researcher 7 10%
Student > Master 6 8%
Professor 3 4%
Other 7 10%
Unknown 31 42%
Readers by discipline Count As %
Neuroscience 12 16%
Pharmacology, Toxicology and Pharmaceutical Science 10 14%
Biochemistry, Genetics and Molecular Biology 7 10%
Medicine and Dentistry 5 7%
Social Sciences 1 1%
Other 3 4%
Unknown 35 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2021.
All research outputs
#7,030,867
of 23,011,300 outputs
Outputs from Methods in molecular biology
#2,112
of 13,157 outputs
Outputs of similar age
#142,232
of 442,319 outputs
Outputs of similar age from Methods in molecular biology
#204
of 1,498 outputs
Altmetric has tracked 23,011,300 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 13,157 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,319 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 1,498 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.