Chapter title |
Blood perfusion of subcutaneous tumours in mice following the application of low-level direct electric current.
|
---|---|
Chapter number | 59 |
Book title |
Oxygen Transport to Tissue XXI
|
Published in |
Advances in experimental medicine and biology, January 1999
|
DOI | 10.1007/978-1-4615-4717-4_59 |
Pubmed ID | |
Book ISBNs |
978-1-4613-7137-3, 978-1-4615-4717-4
|
Authors |
T. Jarm, Y. A. B. D. Wickramasinghe, M. Deakin, M. Čemažar, J. Elder, P. Rolfe, G. Sersa, D. Miklavčič, Jarm, T., Wickramasinghe, Y. A. B. D., Deakin, M., Čemažar, M., Elder, J., Rolfe, P., Sersa, G., Miklavčič, D. |
Abstract |
Electrotherapy with low-level direct electric current has been proved to be an effective local treatment of solid tumours. In the presented study an attempt was made to evaluate the effect of a single treatment with electrotherapy on blood perfusion of solid subcutaneous fibrosarcoma Sa-1 tumours in A/J mice. The tissue-staining method with Patent blue-violet dye, the rubidium extraction technique, and the noninvasive near-infrared spectroscopy method were used for this purpose. Results of all methods indicate that perfusion and subsequently oxygenation of tumours were reduced due to application of electrotherapy. |
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