| Chapter title |
Stimulus specific induction of monocyte chemotactic protein-1 (MCP-1) gene expression.
|
|---|---|
| Chapter number | 8 |
| Book title |
Chemotactic Cytokines
|
| Published in |
Advances in experimental medicine and biology, January 1991
|
| DOI | 10.1007/978-1-4684-6009-4_8 |
| Pubmed ID | |
| Book ISBNs |
978-1-4684-6011-7, 978-1-4684-6009-4
|
| Authors |
Kunkel, S L, Standiford, T, Kasahara, K, Strieter, R M, Kunkel, Steven L., Standiford, Theodore, Kasahara, Keita, Strieter, Robert M. |
| Abstract |
The recruitment of monocytes from the peripheral vasculature to an area of chronic inflammation is a complex phenomenon. This complicated process is likely mediated to a large extent by chemotactic cytokines that are expressed via a cytokine cascade. A number of chronic diseases that are difficult to manage are characterized by a significant infiltrate of monocytes, including sarcoidosis, Wegener's granulomatosis, and tuberculosis. New scientific insight into the mechanisms that lead to early activation events, such as monocyte elicitation, may aid in both better understanding these diverse processes and designing more effective therapies. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 13% |
| Unknown | 7 | 88% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor > Associate Professor | 3 | 38% |
| Student > Ph. D. Student | 2 | 25% |
| Researcher | 1 | 13% |
| Unknown | 2 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 3 | 38% |
| Immunology and Microbiology | 1 | 13% |
| Agricultural and Biological Sciences | 1 | 13% |
| Unknown | 3 | 38% |