Chapter title |
Cloning and expression in Escherichia coli of a protective surface protein from type V group B streptococci.
|
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Chapter number | 143 |
Book title |
Streptococci and the Host
|
Published in |
Advances in experimental medicine and biology, January 1997
|
DOI | 10.1007/978-1-4899-1825-3_143 |
Pubmed ID | |
Book ISBNs |
978-1-4899-1827-7, 978-1-4899-1825-3
|
Authors |
Lachenauer, C S, Madoff, L C, Catherine S. Lachenauer, Lawrence C. Madoff, Lachenauer, Catherine S., Madoff, Lawrence C. |
Abstract |
This report describes a trypsin-resistant laddering protein purified from a type V strain, a serotype of important emerging clinical significance. This protein is present in a majority of type V clinical strains, elicits protective antibody in an animal model, and is cross-reactive with the alpha C protein and R1. The gene encoding this protein has been cloned; preliminary nucleotide sequence analysis reveals significant homology, though not identity, with the alpha C protein gene. These data support the hypothesis that there exists a family of related but distinct GBS surface proteins which may play a role in immunity to GBS infection. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 5 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 2 | 40% |
Professor > Associate Professor | 1 | 20% |
Student > Ph. D. Student | 1 | 20% |
Unknown | 1 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 2 | 40% |
Agricultural and Biological Sciences | 1 | 20% |
Environmental Science | 1 | 20% |
Unknown | 1 | 20% |