Chapter title |
Histone gene expression and chromatin structure during spermatogenesis.
|
---|---|
Chapter number | 4 |
Book title |
The Fate of the Male Germ Cell
|
Published in |
Advances in experimental medicine and biology, January 1997
|
DOI | 10.1007/978-1-4615-5913-9_4 |
Pubmed ID | |
Book ISBNs |
978-1-4613-7711-5, 978-1-4615-5913-9
|
Authors |
D. Doenecke, B. Drabent, C. Bode, B. Bramlage, K. Franke, K. Gavénis, U. Kosciessa, Olaf Witt, Doenecke, D., Drabent, B., Bode, C., Bramlage, B., Franke, K., Gavénis, K., Kosciessa, U., Witt, Olaf |
Abstract |
The chromatin of male germ cells is restructured throughout spermatogenesis. Analysis of differential histone protein patterns at specific stages of spermatogenesis may contribute towards an understanding of the changes in chromatin structure and function during this differentiation process. The most striking changes in histone patterns occur at the stage of pachytene spermatocytes when most of the linker H1 histones are replaced by the testis specific subtype H1t. In addition, replacement of core histone subtypes is observed at this stage. These structural changes precede the reorganization of chromatin at haploid stages when histones are replaced first by transition proteins and then by protamines. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 6% |
Unknown | 15 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor | 3 | 19% |
Student > Master | 3 | 19% |
Researcher | 3 | 19% |
Student > Ph. D. Student | 2 | 13% |
Student > Bachelor | 1 | 6% |
Other | 1 | 6% |
Unknown | 3 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 44% |
Biochemistry, Genetics and Molecular Biology | 2 | 13% |
Nursing and Health Professions | 1 | 6% |
Philosophy | 1 | 6% |
Medicine and Dentistry | 1 | 6% |
Other | 1 | 6% |
Unknown | 3 | 19% |