Chapter title |
Lynestrenol: a progesteronelike agent with immunostimulatory properties.
|
---|---|
Chapter number | 28 |
Book title |
Cancer Chemo- and Immunopharmacology
|
Published in |
Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer, January 1980
|
DOI | 10.1007/978-3-642-81491-4_28 |
Pubmed ID | |
Book ISBNs |
978-3-64-281493-8, 978-3-64-281491-4
|
Authors |
Wybran, J, J. Wybran, Wybran, J. |
Abstract |
Lynestrenol, a synthetic progesteronelike drug, was assessed for its influence upon human leukocyte tests in vitro and in vivo. Lynestrenol markedly enhanced the lymphocyte response to phytohemagglutinin, the mixed lymphocyte culture, the active T-rosette test, the autologous red cell rosettes, and the number of nonadherent cells in the leukocyte adherence inhibition test. All these results indicate a stimulatory effect upon human T-cell function. Lynestrenol also increased monocyte phagocytosis. Lynestrenol delayed the appearance of malignant tumors in hamsters. Finally, lynestrenol, given to lung cancer patients, increased their T-cell functions as evaluated by skin tests. T-cell rosettes, and phytohemagglutinin response. Lynestrenol does possess immunostimulatory properties. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 2 | 67% |
Researcher | 1 | 33% |
Student > Master | 1 | 33% |
Readers by discipline | Count | As % |
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Nursing and Health Professions | 2 | 67% |
Biochemistry, Genetics and Molecular Biology | 1 | 33% |
Agricultural and Biological Sciences | 1 | 33% |