@drmanaf12 PCN resistance in s pneumo is mediated by changes in the PBP, not beta lactamase production. Therefore increasing pcn dose or changing to one with higher pbp affinity would circumvent resistance. BLI doesn’t help with that https://t.co/8UHCse259
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No recent hospitalization and no beta-lactam antibiotics within the past three-to-six months. He did not suffer from HIV or structural lung disease, so there was minimal concern for infection with beta-lactam-resistant strep pneumo https://t.co/9dCrs0cHBA
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RT @bradfop1: Latest book chapter is out 👇https://t.co/Vn1sVvVFOF https://t.co/RR9sHvql3m