Title |
Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions
|
---|---|
Published in |
BMC Ecology and Evolution, June 2008
|
DOI | 10.1186/1471-2148-8-184 |
Pubmed ID | |
Authors |
Tomas A Larsson, Frida Olsson, Gorel Sundstrom, Lars-Gustav Lundin, Sydney Brenner, Byrappa Venkatesh, Dan Larhammar |
Abstract |
One of the many gene families that expanded in early vertebrate evolution is the neuropeptide (NPY) receptor family of G-protein coupled receptors. Earlier work by our lab suggested that several of the NPY receptor genes found in extant vertebrates resulted from two genome duplications before the origin of jawed vertebrates (gnathostomes) and one additional genome duplication in the actinopterygian lineage, based on their location on chromosomes sharing several gene families. In this study we have investigated, in five vertebrate genomes, 45 gene families with members close to the NPY receptor genes in the compact genomes of the teleost fishes Tetraodon nigroviridis and Takifugu rubripes. These correspond to Homo sapiens chromosomes 4, 5, 8 and 10. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Sweden | 2 | 4% |
United States | 2 | 4% |
United Kingdom | 2 | 4% |
Netherlands | 1 | 2% |
Japan | 1 | 2% |
Iceland | 1 | 2% |
Unknown | 46 | 84% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 25% |
Student > Ph. D. Student | 11 | 20% |
Student > Master | 7 | 13% |
Professor | 5 | 9% |
Professor > Associate Professor | 3 | 5% |
Other | 8 | 15% |
Unknown | 7 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 33 | 60% |
Biochemistry, Genetics and Molecular Biology | 7 | 13% |
Medicine and Dentistry | 3 | 5% |
Computer Science | 2 | 4% |
Mathematics | 1 | 2% |
Other | 2 | 4% |
Unknown | 7 | 13% |