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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Antiproliferative activity and synthesis of 8-prenylnaringenin derivatives by demethylation of 7-O- and 4′-O-substituted isoxanthohumols
|
|---|---|
| Published in |
Medicinal Chemistry Research, January 2012
|
| DOI | 10.1007/s00044-011-9967-8 |
| Pubmed ID | |
| Authors |
Mirosław Anioł, Anna Świderska, Monika Stompor, Anna Katarzyna Żołnierczyk |
| Abstract |
Several analogues of 7-O- and 4'-O-substituted isoxanthohumol and 8-prenylnaringenin, the strongest known phytoestrogen and potential anticancerogenic agent, were synthesized. Acyl, alkyl, and allyl derivatives of isoxanthohumol underwent the demethylation process using MgI(2 )× 2Et(2)O in anhydrous THF with the yields of 61-89%. Some of the compounds approached the international criteria of antiproliferative activity (4 μg/ml) for synthetic agents against the human cancer cell lines. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 21 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 24% |
| Student > Master | 5 | 24% |
| Researcher | 4 | 19% |
| Other | 2 | 10% |
| Student > Bachelor | 1 | 5% |
| Other | 0 | 0% |
| Unknown | 4 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 5 | 24% |
| Chemistry | 4 | 19% |
| Immunology and Microbiology | 2 | 10% |
| Medicine and Dentistry | 2 | 10% |
| Computer Science | 1 | 5% |
| Other | 3 | 14% |
| Unknown | 4 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2021.
All research outputs
#4,941,334
of 24,292,134 outputs
Outputs from Medicinal Chemistry Research
#39
of 523 outputs
Outputs of similar age
#40,702
of 249,534 outputs
Outputs of similar age from Medicinal Chemistry Research
#2
of 14 outputs
Altmetric has tracked 24,292,134 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 523 research outputs from this source. They receive a mean Attention Score of 3.5. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,534 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.