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Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, October 2002
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Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases
Published in
Memórias do Instituto Oswaldo Cruz, October 2002
DOI 10.1590/s0074-02762002000700017
Pubmed ID

Fabíola Barbiéri Holetz, Greisiele Lorena Pessini, Neviton Rogério Sanches, Diógenes Aparício Garcia Cortez, Celso Vataru Nakamura, Benedito Prado Dias Filho


Extracts of 13 Brazilian medicinal plants were screened for their antimicrobial activity against bacteria and yeasts. Of these, 10 plant extracts showed varied levels of antibacterial activity. Piper regnellii presented a good activity against Staphylococus aureus and Bacillus subtilis, a moderate activity on Pseudomonas aeruginosa, and a weak activity against Escherichia coli. Punica granatum showed good activity on S. aureus and was inactive against the other standard strains. Eugenia uniflora presented moderate activity on both S. aureus and E. coli. Psidium guajava,Tanacetum vulgare, Arctium lappa, Mikania glomerata, Sambucus canadensis, Plantago major and Erythrina speciosa presented some degree of antibacterial activity. Spilanthes acmella, Lippia alba, and Achillea millefolium were considered inactive. Five of the plant extracts presented compounds with Rf values similar to the antibacterial compounds visible on bioautogram. Of these, three plants belong to the Asteraceae family. This may mean that the same compounds are responsible for the antibacterial activity in these plants. Anticandidal activity was detected in nine plant extracts (P. guajava, E. uniflora, P. granatum, A. lappa, T. vulgare, M. glomerata, L. alba, P. regnellii, and P. major). The results might explain the ethnobotanical use of the studied species for the treatment of various infectious diseases.

Mendeley readers

The data shown below were compiled from readership statistics for 480 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 6 1%
Indonesia 2 <1%
Ecuador 1 <1%
India 1 <1%
Nigeria 1 <1%
United States 1 <1%
Unknown 468 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 91 19%
Student > Master 85 18%
Student > Ph. D. Student 48 10%
Student > Doctoral Student 40 8%
Student > Postgraduate 31 6%
Other 109 23%
Unknown 76 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 137 29%
Chemistry 51 11%
Medicine and Dentistry 37 8%
Pharmacology, Toxicology and Pharmaceutical Science 37 8%
Biochemistry, Genetics and Molecular Biology 35 7%
Other 81 17%
Unknown 102 21%