@AbellJonny no, but it should increase speed of immobilization as it is a true crosslinker in contrast to formaldehyde which doesnt chemically crosslink on these time-scales. also check: https://t.co/2jXAatXBww
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@Roy_Lab_Thinks I look forward reading this in details. It looks very thorough; in line with https://t.co/PFT9mu9KAv. Important here is "cytosolic" proteins - for cytoskeleton and scaffolds we usually extract those and look at a magnificent skeleton...
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@christlet @dozenoaks Also be aware of Kusumi's work suggesting that its not really "fixed" at least for some antigens...."Membrane molecules mobile even after chemical fixation" https://t.co/GcClG52Dv5