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Metaplastic breast cancer: a comparison between the most common histologies with poor immunohistochemistry factors

Overview of attention for article published in BMC Cancer, February 2015
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Title
Metaplastic breast cancer: a comparison between the most common histologies with poor immunohistochemistry factors
Published in
BMC Cancer, February 2015
DOI 10.1186/s12885-015-1079-2
Pubmed ID
Authors

Salim Abraham Barquet-Muñoz, Silvia Patricia Villarreal-Colin, Luis Alonso Herrera-Montalvo, Ernesto Soto-Reyes, Carlos Pérez-Plasencia, Jaime Coronel-Martínez, Delia Pérez-Montiel, Rafael Vázquez-Romo, David Cantú de León

Abstract

Metaplastic carcinoma of the breast (MCB) is a rare histological type of breast cancer. This study aimed to determine whether MCB exhibits shorter overall survival (OS) and disease-free survival (DFS) compared with other histologies that are considered unfavorable. We retrospectively analyzed 157 clinical file records of the Mexico City-based National Institute of Cancerology and compared the clinical characteristics and treatment of 24 patients with MCB, 37 patients with triple-negative invasive lobular carcinoma (TN-ILC), 48 patients with high-grade invasive ductal carcinoma (HG-IDC), and 48 patients with triple-negative invasive ductal carcinoma (TN-IDC), paired by clinical stage and age. We performed a comparative analysis and analyzed OS and DFS using a log-rank test. In patients with MCB, the 5-year DFS was 52.1% (mean, 48.52 months; 95%: 35.32-61.72), and the 5-year OS was 72.2% (mean, 59.77 months; 95% CI: 48.55-71.00). No differences were observed in the DFS of MCB compared with each of the other histologies (MCB vs. HG-IDC, p = 0.865; MCB vs. TN-IDC, p = 0.966, and MCB vs. TN-ILC, p = 0.132). Moreover, no differences were observed when comparing the OS of MCB with that of each of the other histologies (MCB vs. HG-IDC, p = 0.246; MCB vs. TN-IDC, p = 0.255, and MCB vs. TN-ILC, p = 0.387). Neither OS nor DFS differ between patients with MCB and those with other histologies with unfavorable immunohistochemical factors.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Namibia 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 15%
Researcher 3 11%
Student > Doctoral Student 2 7%
Student > Bachelor 2 7%
Lecturer 2 7%
Other 5 19%
Unknown 9 33%
Readers by discipline Count As %
Medicine and Dentistry 8 30%
Nursing and Health Professions 3 11%
Biochemistry, Genetics and Molecular Biology 1 4%
Arts and Humanities 1 4%
Agricultural and Biological Sciences 1 4%
Other 1 4%
Unknown 12 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2015.
All research outputs
#15,325,004
of 22,792,160 outputs
Outputs from BMC Cancer
#4,104
of 8,294 outputs
Outputs of similar age
#150,796
of 254,708 outputs
Outputs of similar age from BMC Cancer
#75
of 149 outputs
Altmetric has tracked 22,792,160 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,294 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 254,708 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 149 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.