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Venom‐derived inhibitors of NaV1.7 channels

Overview of attention for article published in British Journal of Pharmacology, March 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
14 news outlets
blogs
4 blogs
twitter
30 X users
patent
3 patents
facebook
12 Facebook pages

Readers on

mendeley
105 Mendeley
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Title
Venom‐derived inhibitors of NaV1.7 channels
Published in
British Journal of Pharmacology, March 2015
DOI 10.1111/bph.13081
Pubmed ID
Authors

Julie K Klint, Jennifer J Smith, Irina Vetter, Darshani B Rupasinghe, Sing Yan Er, Sebastian Senff, Volker Herzig, Mehdi Mobli, Richard J Lewis, Frank Bosmans, Glenn F King

Abstract

Chronic pain is a serious worldwide health issue, with current analgesics having limited efficacy and dose-limiting side effects. Humans with loss-of-function mutations in the voltage-gated sodium channel NaV 1.7 (hNaV 1.7) are indifferent to pain, making hNaV 1.7 a promising target for analgesic development. Since spider venoms are replete with NaV channel modulators, we examined their potential as a source of hNaV 1.7 inhibitors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 30 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Germany 1 <1%
Unknown 102 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 21%
Student > Master 15 14%
Student > Ph. D. Student 14 13%
Student > Bachelor 11 10%
Other 8 8%
Other 20 19%
Unknown 15 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 26%
Medicine and Dentistry 16 15%
Chemistry 13 12%
Biochemistry, Genetics and Molecular Biology 12 11%
Pharmacology, Toxicology and Pharmaceutical Science 8 8%
Other 10 10%
Unknown 19 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 154. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2022.
All research outputs
#265,817
of 25,397,764 outputs
Outputs from British Journal of Pharmacology
#52
of 7,948 outputs
Outputs of similar age
#2,946
of 272,734 outputs
Outputs of similar age from British Journal of Pharmacology
#3
of 80 outputs
Altmetric has tracked 25,397,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,948 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 272,734 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.