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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Re-evaluation of the pathogenic roles of nonstructural protein 1 and its antibodies during dengue virus infection
|
|---|---|
| Published in |
Journal of Biomedical Science, June 2013
|
| DOI | 10.1186/1423-0127-20-42 |
| Pubmed ID | |
| Authors |
Yung-Chun Chuang, Shu-Ying Wang, Yee-Shin Lin, Hong-Ru Chen, Trai-Ming Yeh |
| Abstract |
Dengue virus (DENV) infection can cause life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Vascular leakage and abnormal hemorrhage are the two major pathogenic changes found in these patients. From previous studies, it is known that both antibodies and cytokines induced in response to DENV infection are involved in the immunopathogenesis of DHF/DSS. However, the role of viral factors during DENV infection remains unclear. Nonstructural protein 1 (NS1), which is secreted in the sera of patients, is a useful diagnostic marker for acute DENV infection. Nevertheless, the roles of NS1 and its antibodies in the pathogenesis of DHF/DSS are unclear. The focus of this review is to evaluate the possible contributions of NS1 and the antibodies it induces to vascular leakage and abnormal hemorrhage during DENV infection, which may provide clues to better understanding the pathogenesis of DHF/DSS. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 1 | <1% |
| Mexico | 1 | <1% |
| France | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 149 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 31 | 20% |
| Student > Ph. D. Student | 23 | 15% |
| Researcher | 18 | 12% |
| Student > Bachelor | 14 | 9% |
| Student > Postgraduate | 7 | 5% |
| Other | 25 | 16% |
| Unknown | 35 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 44 | 29% |
| Medicine and Dentistry | 28 | 18% |
| Biochemistry, Genetics and Molecular Biology | 20 | 13% |
| Immunology and Microbiology | 18 | 12% |
| Social Sciences | 2 | 1% |
| Other | 6 | 4% |
| Unknown | 35 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 September 2015.
All research outputs
#22,759,802
of 25,374,647 outputs
Outputs from Journal of Biomedical Science
#969
of 1,101 outputs
Outputs of similar age
#185,118
of 208,852 outputs
Outputs of similar age from Journal of Biomedical Science
#10
of 11 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,101 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,852 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.