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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Recurring Ethanol Exposure Induces Disinhibited Courtship in Drosophila
|
|---|---|
| Published in |
PLOS ONE, January 2008
|
| DOI | 10.1371/journal.pone.0001391 |
| Pubmed ID | |
| Authors |
Hyun-Gwan Lee, Young-Cho Kim, Jennifer S. Dunning, Kyung-An Han |
| Abstract |
Alcohol has a strong causal relationship with sexual arousal and disinhibited sexual behavior in humans; however, the physiological support for this notion is largely lacking and thus a suitable animal model to address this issue is instrumental. We investigated the effect of ethanol on sexual behavior in Drosophila. Wild-type males typically court females but not males; however, upon daily administration of ethanol, they exhibited active intermale courtship, which represents a novel type of behavioral disinhibition. The ethanol-treated males also developed behavioral sensitization, a form of plasticity associated with addiction, since their intermale courtship activity was progressively increased with additional ethanol experience. We identified three components crucial for the ethanol-induced courtship disinhibition: the transcription factor regulating male sex behavior Fruitless, the ABC guanine/tryptophan transporter White and the neuromodulator dopamine. fruitless mutant males normally display conspicuous intermale courtship; however, their courtship activity was not enhanced under ethanol. Likewise, white males showed negligible ethanol-induced intermale courtship, which was not only reinstated but also augmented by transgenic White expression. Moreover, inhibition of dopamine neurotransmission during ethanol exposure dramatically decreased ethanol-induced intermale courtship. Chronic ethanol exposure also affected a male's sexual behavior toward females: it enhanced sexual arousal but reduced sexual performance. These findings provide novel insights into the physiological effects of ethanol on sexual behavior and behavioral plasticity. |
X Demographics
The data shown below were collected from the profiles of 202 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 51 | 25% |
| Chile | 13 | 6% |
| Argentina | 5 | 2% |
| Colombia | 4 | 2% |
| Venezuela, Bolivarian Republic of | 2 | <1% |
| Peru | 2 | <1% |
| United Kingdom | 2 | <1% |
| Comoros | 1 | <1% |
| Antigua and Barbuda | 1 | <1% |
| Other | 11 | 5% |
| Unknown | 110 | 54% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 186 | 92% |
| Scientists | 11 | 5% |
| Practitioners (doctors, other healthcare professionals) | 5 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 4% |
| Australia | 2 | 2% |
| Switzerland | 1 | <1% |
| Ghana | 1 | <1% |
| Uganda | 1 | <1% |
| Germany | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Other | 5 | 5% |
| Unknown | 89 | 83% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 29 | 27% |
| Researcher | 21 | 20% |
| Student > Bachelor | 13 | 12% |
| Student > Master | 13 | 12% |
| Professor > Associate Professor | 10 | 9% |
| Other | 9 | 8% |
| Unknown | 12 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 51 | 48% |
| Neuroscience | 15 | 14% |
| Biochemistry, Genetics and Molecular Biology | 13 | 12% |
| Environmental Science | 4 | 4% |
| Psychology | 3 | 3% |
| Other | 8 | 7% |
| Unknown | 13 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 207. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2022.
All research outputs
#194,983
of 25,909,281 outputs
Outputs from PLOS ONE
#2,880
of 226,020 outputs
Outputs of similar age
#420
of 170,429 outputs
Outputs of similar age from PLOS ONE
#3
of 204 outputs
Altmetric has tracked 25,909,281 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 226,020 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,429 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 204 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.