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Activation of the Wnt/β-Catenin Signaling Pathway by Mechanical Ventilation Is Associated with Ventilator-Induced Pulmonary Fibrosis in Healthy Lungs

Overview of attention for article published in PLOS ONE, September 2011
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Title
Activation of the Wnt/β-Catenin Signaling Pathway by Mechanical Ventilation Is Associated with Ventilator-Induced Pulmonary Fibrosis in Healthy Lungs
Published in
PLOS ONE, September 2011
DOI 10.1371/journal.pone.0023914
Pubmed ID
Authors

Jesús Villar, Nuria E. Cabrera, Francisco Valladares, Milena Casula, Carlos Flores, Lluís Blanch, María Elisa Quilez, Norberto Santana-Rodríguez, Robert M. Kacmarek, Arthur S. Slutsky

Abstract

Mechanical ventilation (MV) with high tidal volumes (V(T)) can cause or aggravate lung damage, so-called ventilator induced lung injury (VILI). The relationship between specific mechanical events in the lung and the cellular responses that result in VILI remains incomplete. Since activation of Wnt/β-catenin signaling has been suggested to be central to mechanisms of lung healing and fibrosis, we hypothesized that the Wnt/β-catenin signaling plays a role during VILI.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 13%
Researcher 5 13%
Other 4 10%
Professor > Associate Professor 4 10%
Student > Postgraduate 3 8%
Other 10 26%
Unknown 8 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 21%
Biochemistry, Genetics and Molecular Biology 7 18%
Medicine and Dentistry 4 10%
Social Sciences 2 5%
Nursing and Health Professions 2 5%
Other 7 18%
Unknown 9 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2011.
All research outputs
#20,145,561
of 22,651,245 outputs
Outputs from PLOS ONE
#172,535
of 193,366 outputs
Outputs of similar age
#116,104
of 126,287 outputs
Outputs of similar age from PLOS ONE
#2,318
of 2,506 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,366 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 126,287 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2,506 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.