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Engineering microbes for tolerance to next-generation biofuels

Overview of attention for article published in Biotechnology for Biofuels, January 2011
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Mentioned by

twitter
5 tweeters

Readers on

mendeley
406 Mendeley
citeulike
4 CiteULike
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Title
Engineering microbes for tolerance to next-generation biofuels
Published in
Biotechnology for Biofuels, January 2011
DOI 10.1186/1754-6834-4-32
Pubmed ID
Authors

Mary J Dunlop

Abstract

A major challenge when using microorganisms to produce bulk chemicals such as biofuels is that the production targets are often toxic to cells. Many biofuels are known to reduce cell viability through damage to the cell membrane and interference with essential physiological processes. Therefore, cells must trade off biofuel production and survival, reducing potential yields. Recently, there have been several efforts towards engineering strains for biofuel tolerance. Promising methods include engineering biofuel export systems, heat shock proteins, membrane modifications, more general stress responses, and approaches that integrate multiple tolerance strategies. In addition, in situ recovery methods and media supplements can help to ease the burden of end-product toxicity and may be used in combination with genetic approaches. Recent advances in systems and synthetic biology provide a framework for tolerance engineering. This review highlights recent targeted approaches towards improving microbial tolerance to next-generation biofuels with a particular emphasis on strategies that will improve production.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 406 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 18 4%
Belgium 2 <1%
India 2 <1%
Netherlands 2 <1%
Brazil 1 <1%
France 1 <1%
Kenya 1 <1%
Indonesia 1 <1%
Sweden 1 <1%
Other 6 1%
Unknown 371 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 114 28%
Researcher 69 17%
Student > Master 66 16%
Student > Bachelor 48 12%
Student > Doctoral Student 23 6%
Other 65 16%
Unknown 21 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 209 51%
Biochemistry, Genetics and Molecular Biology 69 17%
Engineering 45 11%
Chemical Engineering 19 5%
Chemistry 8 2%
Other 25 6%
Unknown 31 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2011.
All research outputs
#4,533,950
of 14,742,972 outputs
Outputs from Biotechnology for Biofuels
#370
of 1,123 outputs
Outputs of similar age
#31,727
of 99,636 outputs
Outputs of similar age from Biotechnology for Biofuels
#4
of 9 outputs
Altmetric has tracked 14,742,972 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,123 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 99,636 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.