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Sp1 and c-Myc modulate drug resistance of leukemia stem cells by regulating survivin expression through the ERK-MSK MAPK signaling pathway

Overview of attention for article published in Molecular Cancer, March 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

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1 X user
patent
1 patent

Citations

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87 Dimensions

Readers on

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69 Mendeley
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Title
Sp1 and c-Myc modulate drug resistance of leukemia stem cells by regulating survivin expression through the ERK-MSK MAPK signaling pathway
Published in
Molecular Cancer, March 2015
DOI 10.1186/s12943-015-0326-0
Pubmed ID
Authors

Yi Zhang, Hai-xuan Chen, Shu-yan Zhou, Shao-xiang Wang, Kai Zheng, Dan-dan Xu, Yu-ting Liu, Xiao-yan Wang, Xiao Wang, Hai-zhao Yan, Li Zhang, Qiu-ying Liu, Wan-qun Chen, Yi-fei Wang

Abstract

Acute myeloid leukemia (AML) is initiated and maintained by a subset of self-renewing leukemia stem cells (LSCs), which contribute to the progression, recurrence and therapeutic resistance of leukemia. However, the mechanisms underlying the maintenance of LSCs drug resistance have not been fully defined. In this study, we attempted to elucidate the mechanisms of LSCs drug resistance.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 1%
Unknown 68 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 22%
Researcher 8 12%
Student > Bachelor 7 10%
Other 6 9%
Student > Master 6 9%
Other 10 14%
Unknown 17 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 25%
Agricultural and Biological Sciences 13 19%
Immunology and Microbiology 4 6%
Medicine and Dentistry 4 6%
Engineering 2 3%
Other 10 14%
Unknown 19 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2023.
All research outputs
#7,414,573
of 25,540,105 outputs
Outputs from Molecular Cancer
#606
of 1,935 outputs
Outputs of similar age
#79,819
of 274,409 outputs
Outputs of similar age from Molecular Cancer
#13
of 70 outputs
Altmetric has tracked 25,540,105 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,935 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,409 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.