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MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes

Overview of attention for article published in Arthritis Research & Therapy, March 2015
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Citations

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Title
MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes
Published in
Arthritis Research & Therapy, March 2015
DOI 10.1186/s13075-015-0556-y
Pubmed ID
Authors

Fotini Kostopoulou, Konstantinos N Malizos, Ioanna Papathanasiou, Aspasia Tsezou

Abstract

Several studies have shown that osteoarthritis (OA) is strongly associated with metabolic related disorders, highlighting OA as the fifth component of the Metabolic Syndrome (MetS). Based on our previous findings on dysregulation of cholesterol homeostasis in OA, we were prompted to investigate whether microRNA-33a (miR-33a), one of the master regulators of cholesterol and fatty acid metabolism, plays a key role in OA pathogenesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 77 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 15%
Researcher 11 14%
Student > Master 10 13%
Student > Bachelor 7 9%
Student > Doctoral Student 5 6%
Other 15 19%
Unknown 18 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 19%
Medicine and Dentistry 14 18%
Agricultural and Biological Sciences 10 13%
Nursing and Health Professions 6 8%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 8 10%
Unknown 22 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2016.
All research outputs
#15,327,280
of 22,796,179 outputs
Outputs from Arthritis Research & Therapy
#2,190
of 2,976 outputs
Outputs of similar age
#152,927
of 257,883 outputs
Outputs of similar age from Arthritis Research & Therapy
#40
of 63 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,976 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 257,883 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.