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Nasal carriage of Staphylococcus aureus in healthy humans with different levels of contact with animals in Tunisia: genetic lineages, methicillin resistance, and virulence factors

Overview of attention for article published in European Journal of Clinical Microbiology & Infectious Diseases, November 2010
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Title
Nasal carriage of Staphylococcus aureus in healthy humans with different levels of contact with animals in Tunisia: genetic lineages, methicillin resistance, and virulence factors
Published in
European Journal of Clinical Microbiology & Infectious Diseases, November 2010
DOI 10.1007/s10096-010-1109-6
Pubmed ID
Authors

K. Ben Slama, H. Gharsa, N. Klibi, A. Jouini, C. Lozano, E. Gómez-Sanz, M. Zarazaga, A. Boudabous, C. Torres

Abstract

Nasal swabs of 423 healthy humans who showed different levels of contact with animals (frequent, 168; sporadic, 94; no contact, 161) were obtained in Tunisia (2008-2009), and 99 of them presented other associated risk factors. Methicillin-resistant Staphylococcus aureus (MRSA) was detected in one of these 423 samples (0.24%), retrieved from a veterinarian. The MRSA isolate was mecA-positive, typed as ST80-t203-SCCmecIVc-agrIII, and contained tet(K), ant(6)-Ia, and aph(3')-IIIa genes encoding tetracycline, streptomycin, and kanamycin resistance, respectively. This MRSA isolate also contained the lukF/lukS virulence gene encoding Panton-Valentine leukocidin. Fifty-four (12.8%) additional nasal samples contained methicillin-susceptible S. aureus (MSSA) and one isolate/sample was characterized. A high diversity of spa types (n = 43; 4 new) and pulsed-field gel electrophoresis (PFGE) types (n = 37) was detected among the 55 recovered S. aureus strains. The percentages of antimicrobial resistance/detected resistance genes were as follows: tetracycline [22%/tet(K)-tet(L)-tet(M)], erythromycin [5%/msrA], ciprofloxacin [14.5%], trimethoprim-sulfamethoxazole [2%/dfrA], streptomycin [11%/ant(6)-Ia], kanamycin [7%/aph(3')-IIIa], amikacin [5%], and chloramphenicol [2%]. Four and two isolates carried the lukF/lukS and eta and/or etb genes, respectively, and always in individuals with contact with animals. Eleven isolates carried the tst gene and were recovered from individuals with different levels of contact with animals.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
India 1 1%
Denmark 1 1%
Belgium 1 1%
Unknown 65 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 28%
Student > Master 9 13%
Student > Doctoral Student 8 12%
Professor 6 9%
Student > Ph. D. Student 6 9%
Other 10 14%
Unknown 11 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 23%
Medicine and Dentistry 14 20%
Immunology and Microbiology 13 19%
Veterinary Science and Veterinary Medicine 3 4%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 2 3%
Unknown 18 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 September 2011.
All research outputs
#20,147,309
of 22,653,392 outputs
Outputs from European Journal of Clinical Microbiology & Infectious Diseases
#2,402
of 2,767 outputs
Outputs of similar age
#95,399
of 100,839 outputs
Outputs of similar age from European Journal of Clinical Microbiology & Infectious Diseases
#16
of 16 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,767 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 100,839 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.