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NGF and therapeutic prospective: what have we learned from the NGF transgenic models?

Overview of attention for article published in Annali dell'Istituto Superiore di Sanità, January 2015
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1 tweeter

Citations

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4 Dimensions

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Title
NGF and therapeutic prospective: what have we learned from the NGF transgenic models?
Published in
Annali dell'Istituto Superiore di Sanità, January 2015
DOI 10.4415/ann_15_01_03
Pubmed ID
Authors

Aloe, Luigi, Rocco, Maria Luisa

Abstract

It has been shown that topical nerve growth factor (NGF) administration induces healing action on human cutaneous, corneal and pressure ulcers, glaucoma, maculopathy and retinitis pigmentosa suggesting a therapeutic potential of NGF in human ophthalmology and cutaneous ulcers. A similar therapeutic suggestion has emerged for the NGF gene therapy of Alzheimer's disease and ischemic heart injury. Moreover, over the last few years, the role and biological properties of NGF have also been investigated with transgenic mice over-expressing and down-expressing NGF. However, the results obtained with these transgenic mice seem suitable to confirm and/or support the evidence obtained with exogenous administration of NGF regarding the suggested clinical potentiality of NGF. The aim of the present brief review is to report and comment on these two different findings of NGF's healing properties.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 7%
Unknown 14 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 27%
Student > Master 3 20%
Researcher 3 20%
Student > Doctoral Student 2 13%
Student > Postgraduate 1 7%
Other 0 0%
Unknown 2 13%
Readers by discipline Count As %
Medicine and Dentistry 3 20%
Pharmacology, Toxicology and Pharmaceutical Science 2 13%
Neuroscience 2 13%
Psychology 1 7%
Agricultural and Biological Sciences 1 7%
Other 4 27%
Unknown 2 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2015.
All research outputs
#2,642,995
of 4,982,163 outputs
Outputs from Annali dell'Istituto Superiore di Sanità
#29
of 89 outputs
Outputs of similar age
#87,332
of 150,640 outputs
Outputs of similar age from Annali dell'Istituto Superiore di Sanità
#1
of 1 outputs
Altmetric has tracked 4,982,163 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 89 research outputs from this source. They receive a mean Attention Score of 1.8. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 150,640 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them