Title |
Sleep disorders in children with brain tumors: a pilot study based on a sleep disorder questionnaire
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Published in |
Child's Nervous System, April 2018
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DOI | 10.1007/s00381-018-3809-7 |
Pubmed ID | |
Authors |
Chiara Pilotto, Eva Passone, Elisa Coassin, Silvia Birri, Ettore Bidoli, Giovanni Crichiutti, Paola Cogo, Maurizio Mascarin |
Abstract |
The aim of this study is to compare the prevalence of sleep disorders (SD) between children treated for brain tumors and healthy children, and to define the type of SD. A case-control study was performed from October 2014 to April 2015. Inclusion criteria were patients between 2 and 16 years with "cases" defined as children affected by central nervous system tumors at least 3 months after the end of treatment (surgery and/or radiotherapy and/or chemotherapy) at the time of evaluation and "controls" as healthy children. Children's sleep quality was assessed with a questionnaire administered to parents (Child's Sleep Habits Questionnaire, CSHQ). A total score greater than 41 is suggestive for the presence of disturbed sleep. The risk of SD was estimated by the odds ratio (OR) and their 95% confidence intervals (95% CI) through logistic regression models. Twenty-nine cases and 87 controls (in a 1:3 model) were enrolled, for a total of 116 subjects. The prevalence of SD resulted of 82.8% among cases and 64.4% in controls. A statistically significant difference between the two groups (OR 2.65; 95% CI 0.92-7.65) was not reached. Analyzing singular disturbances, parasomnias and night awakenings showed a statistically significant difference between the two groups (OR 4.32; 95% CI 1.08-17.34). Our study revealed a trend toward SD in children with brain tumor when compared to healthy population. Hovewer, analyzing specific subtypes of SD some significant differences were obtained. A significant difference was obtained only for specific subtypes of SD. Further investigations could better define the real burden of SD. |
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Portugal | 1 | 33% |
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United States | 1 | 33% |
Demographic breakdown
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Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
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Unknown | 37 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 5 | 14% |
Other | 4 | 11% |
Student > Postgraduate | 3 | 8% |
Researcher | 3 | 8% |
Student > Ph. D. Student | 3 | 8% |
Other | 7 | 19% |
Unknown | 12 | 32% |
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Nursing and Health Professions | 4 | 11% |
Psychology | 3 | 8% |
Business, Management and Accounting | 1 | 3% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 4 | 11% |
Unknown | 12 | 32% |