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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A FYVE zinc finger domain protein specifically links mRNA transport to endosome trafficking
|
|---|---|
| Published in |
eLife, May 2015
|
| DOI | 10.7554/elife.06041 |
| Pubmed ID | |
| Authors |
Thomas Pohlmann, Sebastian Baumann, Carl Haag, Mario Albrecht, Michael Feldbrügge |
| Abstract |
An emerging theme in cellular logistics is the close connection between mRNA and membrane trafficking. A prominent example is the microtubule-dependent transport of mRNAs and associated ribosomes on endosomes. This coordinated process is crucial for correct septin filamentation and efficient growth of polarised cells such as fungal hyphae. Despite detailed knowledge on the key RNA-binding protein and the molecular motors involved, it is unclear how mRNAs are connected to membranes during transport. Here, we identify a novel factor containing a FYVE zinc finger domain for interaction with endosomal lipids and a new PAM2-like domain required for interaction with the MLLE domain of the key RNA-binding protein. Consistently, loss of this FYVE domain protein leads to specific defects in mRNA, ribosome and septin transport without affecting general functions of endosomes or their movement. Hence, this is the first endosomal component specific for mRNP trafficking uncovering a new mechanism to couple mRNPs to endosomes. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 30% |
| Georgia | 1 | 10% |
| India | 1 | 10% |
| Austria | 1 | 10% |
| United Kingdom | 1 | 10% |
| Unknown | 3 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 5 | 50% |
| Members of the public | 5 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 106 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 25% |
| Student > Master | 11 | 10% |
| Researcher | 9 | 8% |
| Professor > Associate Professor | 9 | 8% |
| Student > Bachelor | 8 | 7% |
| Other | 21 | 20% |
| Unknown | 22 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 35% |
| Biochemistry, Genetics and Molecular Biology | 30 | 28% |
| Neuroscience | 11 | 10% |
| Unspecified | 4 | 4% |
| Chemistry | 2 | 2% |
| Other | 3 | 3% |
| Unknown | 20 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2015.
All research outputs
#4,411,009
of 22,805,349 outputs
Outputs from eLife
#8,643
of 13,819 outputs
Outputs of similar age
#56,224
of 265,512 outputs
Outputs of similar age from eLife
#113
of 208 outputs
Altmetric has tracked 22,805,349 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,819 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 36.9. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,512 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 208 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.