Title |
T-helper 17-related cytokines and IgE antibodies during hepatitis A virus infection in children
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Published in |
Memórias do Instituto Oswaldo Cruz, March 2015
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DOI | 10.1590/0074-02760140309 |
Pubmed ID | |
Authors |
Jorge L Trujillo-Ochoa, Karla F Corral-Jara, Griselda Escobedo-Meléndez, Mauricio Realpe, Arturo Panduro, Sonia Roman, Nora A Fierro |
Abstract |
We determined the serum IgE levels and T-helper (Th)17-related cytokines during distinct hepatitis A virus (HAV)-induced clinical courses in children. A significantly higher concentration of macrophage inflammatory protein 3α, interleukin (IL)-17E and IL-17F in HAV-infected children with intermediate liver injury compared with those with minor liver damage was found. A reduction in the IgE levels in those patients who showed the highest levels of IL-17F in the group of intermediate liver injury was found. The data suggested that the Th17-related profile is associated with the severity of HAV infection and might play a role on the modulation achieved by HAV during allergies. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 1 | 6% |
Unknown | 17 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 3 | 17% |
Student > Bachelor | 2 | 11% |
Other | 2 | 11% |
Researcher | 2 | 11% |
Student > Postgraduate | 2 | 11% |
Other | 3 | 17% |
Unknown | 4 | 22% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 4 | 22% |
Medicine and Dentistry | 3 | 17% |
Agricultural and Biological Sciences | 2 | 11% |
Immunology and Microbiology | 2 | 11% |
Materials Science | 1 | 6% |
Other | 0 | 0% |
Unknown | 6 | 33% |