Title |
Biofilm production by multiresistant Corynebacterium striatumassociated with nosocomial outbreak
|
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Published in |
Memórias do Instituto Oswaldo Cruz, April 2015
|
DOI | 10.1590/0074-02760140373 |
Pubmed ID | |
Authors |
Cassius de Souza, Yuri Vieira Faria, Lincoln de Oliveira Sant’Anna, Vanilda Gonçalves Viana, Sérgio Henrique Seabra, Mônica Cristina de Souza, Verônica Viana Vieira, Raphael Hirata, Lílian de Oliveira Moreira, Ana Luíza de Mattos-Guaraldi |
Abstract |
Corynebacterium striatum is a potentially pathogenic microorganism that causes nosocomial outbreaks. However, little is known about its virulence factors that may contribute to healthcare-associated infections (HAIs). We investigated the biofilm production on abiotic surfaces of multidrug-resistant (MDR) and multidrug-susceptible (MDS) strains of C. striatum of pulsed-field gel electrophoresis types I-MDR, II-MDR, III-MDS and IV-MDS isolated during a nosocomial outbreak in Rio de Janeiro, Brazil. The results showed that C. striatum was able to adhere to hydrophilic and hydrophobic abiotic surfaces. The C. striatum 1987/I-MDR strain, predominantly isolated from patients undergoing endotracheal intubation procedures, showed the greatest ability to adhere to all surfaces. C. striatum bound fibrinogen to its surface, which contributed to biofilm formation. Scanning electron microscopy showed the production of mature biofilms on polyurethane catheters by all pulsotypes. In conclusion, biofilm production may contribute to the establishment of HAIs caused by C. striatum. |
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Demographic breakdown
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Scientists | 1 | 100% |
Mendeley readers
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Student > Master | 11 | 12% |
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Researcher | 9 | 10% |
Student > Postgraduate | 7 | 8% |
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