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A randomized controlled trial to investigate the influence of low dose radiotherapy on immune stimulatory effects in liver metastases of colorectal cancer

Overview of attention for article published in BMC Cancer, September 2011
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1 tweeter

Citations

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37 Mendeley
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Title
A randomized controlled trial to investigate the influence of low dose radiotherapy on immune stimulatory effects in liver metastases of colorectal cancer
Published in
BMC Cancer, September 2011
DOI 10.1186/1471-2407-11-419
Pubmed ID
Authors

Christoph Reissfelder, Carmen Timke, Hubertus Schmitz-Winnenthal, Nuh N Rahbari, Moritz Koch, Felix Klug, Falk Roeder, Lutz Edler, Jürgen Debus, Markus W Büchler, Philipp Beckhove, Peter E Huber, Jürgen Weitz

Abstract

Insufficient migration and activation of tumor specific effector T cells in the tumor is one of the main reasons for inadequate host anti-tumor immune response. External radiation seems to induce inflammation and activate the immune response. This phase I/II clinical trial aims to evaluate whether low dose single fraction radiotherapy can improve T cell associated antitumor immune response in patients with colorectal liver metastases.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 41%
Student > Ph. D. Student 10 27%
Student > Master 7 19%
Unspecified 1 3%
Lecturer 1 3%
Other 2 5%
Unknown 1 3%
Readers by discipline Count As %
Medicine and Dentistry 19 51%
Agricultural and Biological Sciences 9 24%
Immunology and Microbiology 3 8%
Biochemistry, Genetics and Molecular Biology 2 5%
Unspecified 1 3%
Other 0 0%
Unknown 3 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2011.
All research outputs
#2,946,629
of 3,684,317 outputs
Outputs from BMC Cancer
#1,386
of 1,820 outputs
Outputs of similar age
#43,735
of 64,882 outputs
Outputs of similar age from BMC Cancer
#51
of 82 outputs
Altmetric has tracked 3,684,317 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,820 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 64,882 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 82 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.