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Heart regeneration, stem cells, and cytokines

Overview of attention for article published in Regenerative Medicine Research, April 2014
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3 X users
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1 Facebook page

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62 Mendeley
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Title
Heart regeneration, stem cells, and cytokines
Published in
Regenerative Medicine Research, April 2014
DOI 10.1186/2050-490x-2-6
Pubmed ID
Authors

Na Li, Chuan Wang, LiXin Jia, Jie Du

Abstract

The human heart has limited regenerative capacity, which makes the reparative response after the cardiac infarction quite challenging. During the last decade, stem cells have become promising candidates for heart repair, owing to their potent differentiation capacity and paracrine cytokine secretion. Among the different types of stem cells, mesenchymal stem cells have high proliferative potential and secrete numerous cytokines, growth factors, and microRNAs. The paracrine cytokines play important roles in cardiac regeneration, neovascularization, anti-apoptosis, and anti-remodeling mechanisms, among others. This review summarizes the cytokines secreted by stem cells and their relative signaling pathways, which represent key mechanisms for heart regeneration and may serve as a promising future therapeutic strategy for myocardial infarction patients.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 62 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 23%
Student > Ph. D. Student 10 16%
Student > Bachelor 10 16%
Researcher 7 11%
Student > Postgraduate 5 8%
Other 9 15%
Unknown 7 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 32%
Medicine and Dentistry 13 21%
Biochemistry, Genetics and Molecular Biology 8 13%
Engineering 4 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 6 10%
Unknown 9 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2017.
All research outputs
#16,721,208
of 25,371,288 outputs
Outputs from Regenerative Medicine Research
#16
of 25 outputs
Outputs of similar age
#137,475
of 238,765 outputs
Outputs of similar age from Regenerative Medicine Research
#2
of 3 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25 research outputs from this source. They receive a mean Attention Score of 2.3. This one scored the same or higher as 9 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,765 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.